How are mineral amino acid chelates in nanominerals absorbed?
Because the body is very efficient at absorbing individual amino acids, it allows a mineral chelated to an amino acid to be carried along with its amino acid ligand into the intestinal cell during absorption. Clinical studies have shown that the intestinal absorption pathway of an amino acid chelate is different than the absorption of minerals from inorganic metal salts. As the amino acid chelate approaches the intestinal wall, it remains the same molecule that was ingested. The chelate does not require digestion prior to absorption due to its size. The glycine amino acid chelate, for example, is stable and does not become disassociated in the stomach.
Along the intestinal wall are finger-like projections called villi. The villi increase the surface area for the amino acid chelate to be absorbed. On each villus are microvilli. It is through the membranes of the cell walls of the microvilli that the amino acid chelate is absorbed. Once inside the cells, the components of the chelate are used by the body as any mineral and amino acid would be after absorption. Chelating with ligands like glycine to form a glycine amino acid chelate makes more of the ingested minerals available for metabolic purposes (growth, reproduction, immunity, etc.) compared to other inorganic and organic mineral forms (metal proteinates or amino acid complexes).
Numerous clinical studies have proven that Albion's metal amino acid chelates are better absorbed than inorganic minerals, metal proteinates, or amino acid complexes. In fact the absorption pathway of a metal proteinate is unknown. Amino acid complexes are hydrolyzed in the stomach and intestine, and the minerals are absorbed similarly to inorganic metal salts.
Due to pH constraints, minerals from amino acid complexes or digested metal proteinates can only be absorbed in the upper portion of the small intestine (duodenum). Proteinates do require digestion prior to absorption due their large size. Complexes are not stable compounds and will disassociate in the stomach.
What are chelated minerals?
"Chelated minerals" is a scientific term referring to a very specific molecular reaction that takes place between a molecule and a nutritional mineral. Chelation is a natural process that happens in the gut to facilitate transportation of nutritional minerals across the intestinal wall as a part of digestion. As our body is not very efficient at producing chelated minerals, we look to these mineral forms in nutritional supplements to assure greater efficiencies of absorption.
At Albion, we create these chelated minerals in our laboratories under very carefully controlled conditions. Albions most commonly used molecule to create organic chelated nutritional minerals is glycine. Glycine is an amino acid that the body readily identifies and which is efficiently absorbed across the intestinal wall. Albions glycine amino acid chelates are actually small enough to be transported right into the cell itself.
For more explanation see Why Chelated Minerals are Not Created Equal.
Why are minerals important to the body?
Each of the following systems in the body utilize minerals. Research shows that imbalances or deficiencies in mineral nutrition can affect these systems:
Immune System: Copper (Cu), Zinc (Zn), Iron (Fe) and Selenium (Se)
Energy Production:Magnesium (Mg), Phosphorus (P) and Manganese (Mn)
Hormone System:Iron (Fe), Manganese (Mn), Zinc (Zn), Copper (Cu), Magnesium (Mg) and Potassium (K)
Vitamin Production: Cobalt (Co)
Blood Production: Copper (Cu) and Iron (Fe)
Enzyme Systems: Zinc (Zn), Copper (Cu), Potassium (K), Manganese (Mn), Magnesium (Mg), Iron (Fe), Calcium (Ca) and Molybdenum (Mo)
Skeletal System:Calcium (Ca), Magnesium (Mg), Zinc (Zn), Manganese (Mn), Boron (B) and Phosphorus (P)
What is bioavailability?
Bioavailability is the measure of the amount of an ingested nutrient that is absorbed and made available to the body for metabolic use. Bioavailability is important because nutrients must be absorbed to be available to various body systems for growth, maintenance of body tissues, reproduction, and other performance factors. No matter how high the nutrient levels or how well formulated the product, if the nutrient is not bioavailable for use by body tissue, then money and effort have been wasted.
What are nutritional minerals?
As simple as it may seem, this question is the first step in examining the role of minerals in nutrition. The dictionary describes minerals as solid, crystalline substances (diamond, copper, quartz, etc.) not of animal or vegetable origin. The key words are "not of animal or vegetable origin" meaning they are inorganic elements. Because minerals intended for nutritional purposes cannot be synthesized by the body, they must be utilized as natural elements - they must be eaten and successfully absorbed.
In context, we are talking about nutritional minerals. Nutritional minerals are a small sub group of the above broad, general statement. Though nutritional mineral requirements differ between plants and animals, generally the nutritional minerals are regarded as: Boron, Magnesium, Phosphorous, Sulfur, Potassium, Calcium, Vanadium, Chromium, Manganese, Iron, Cobalt, Copper, Zinc, Selenium, Molybdenum and Iodine.
How does one evaluate nanominerals chelates against the other mineral forms?
What is stability and why is it important?
Simply mixing inorganic minerals with amino acids in a liquid or dry mixture does not allow chelation to occur. Simple ionic and hydrogen bonding of minerals to amino acids does not produce a stable product. Minerals and amino acids must be processed according to a specific formula in order to create a stable (coordinate covalent) bond, which is essential for greater bioavailability. Albion's patented processes assure that this bond is formed Many products on the market are reported to be chelates. Some of these products are only complexed mixtures of minerals and proteins and cannot be identified as true amino acid chelates. These complexed mixtures lose stability during digestion, compromising the availability of the mineral nutrient. When looking for available minerals, look for Albion chelates. We guarantee purity and stability.