About NanoSorb®
NanoSorb® is BioPharma Scientific's trademark for its patented delivery system proven to significantly enhance bioavailability.
NanoSorb® mimics our bodies own strategy in creating sub micron sized liposomes as carriers for otherwise poorly soluble, and therefore poorly absorbed, nutrients.
|
Liposomes, "fat bodies" in Greek, have been known within the scientific community for decades. Indeed, the normal human digestion of fats includes our bodies making these bioavailable by encapsulating them in liposomes (150 nm) or emulsifying them in even smaller mycelles (<50 nm). Since the mid-1960's liposomes have been recognized as safe and effective carriers of biologically active ingredients to target specific sites of action in a variety of therapeutic applications. Because liposomes are uniquely versatile, they have been long been safely utilized in such diverse applications as pharmaceuticals, cancer therapy, gene manipulation, and cosmetics. In 2005, Biopharma garnered the exclusive right to an improved, patented liposome technology formula for use in the nutraceutical arena. We call this liposome NanoSorb®.
NanoSorb®
NanoSorb® is an improved liposomal delivery technology, used in medicines and skin care products following its development in the early 1990’s. The NanoSorb® technology forms liposomes, ranging from 50 to 500 nm in diameter, that encapsulate spontaneously upon the addition of water, without standard heating, cooling and agitation methods used for ordinary liposomes! Our new patented technology is therefore much more economical.
NanoSorb®'s liposomal technology can encapsulate both hydrophobic and hydrophilic ingredients. They solubilize otherwise poorly absorbable small molecules like phytonutrients, peptides, and proteins for both oral dosing and topical application.
|
| 
|
| 
|
Microscopic Pictures of NanoSorb® Liposomes
NanoSorb® liposomes can be unilamellar or multilamellar. Pictured below is phase contrast optical microscopy of NanoSorb® spontaneous liposome formation 10 minutes after addition of water. Multilamellar vesicles (left) and large unilamellar vesicle (right)
|
As NanoSorb® technology is unique, forming liposomes (50 – 500 nm) that encapsulate spontaneously upon the addition of water, there is no need for "old tech" heating, cooling, pressure, sonication, filtration and/or agitation methods used for ordinary liposomes! Our new patented technology provides minimal potential for degradation, especially with highly sensitive bio-active nutraceuticals.
|
| 
|
The NanoSorb® molecule encapsulation percentage is greater than ordinary liposomes
NanoSorb® also encapsulates ingredients more effectively then "old tech" liposomes, as the chart below demonstrates.
|
| 
Comparative encapsulation % profile of CoQ10 for 3 months at room temperature |
NanoSorb® bioavailability is greater than Liposomes
CoQ-10 nanoencapsulated in the NanoSorb® molecules is also are more bioavailable than liposomal CoQ-10
|
| 
Comparative studies show nanoSomes have a better release profile than Liposomes |
Topical Penetration Study: Penetration = Efficacy
The NanoSorb® delivery system also delivers a greater amount of the active ingredients through the skin as compared to conventional vehicles.
Improved Dermal Penetration
|
| 
Comparative study showing the amount of caffeine that penetrates through the layers of skin at eight hours. |
NanoSorb®
NanoSorb® is a new, patented delivery system designed for efficacy, flexibility, and utility. NanoSorb® represents a breakthrough in the lipid-based fill of soft gelatin and two-piece hard shell capsules. This technology incorporates active ingredients encapsulated in NanoSomes into a self-emulsifying liquid complex that is then enrobed into a capsule for convenient oral administration.NanoSorb® has been proven to enhance the absorption of orally administered vitamins and nutritional ingredients.
|
| 
|
NanoSorb® equals Bio-availability
NanoSorb® delivery system is especially suited for oral delivery of pharmaceuticals and nutraceuticals with poor bioavailability such as newly discovered drugs, proteins and peptides that are not soluble with conventional technologies.
|
| 
|
NanoSorb® active ingredients can be taken orally or with topical administration
The NanoSorb® Advantage
NanoSorb® is one of the most significant developments in oral pharmaceutics within the last decade.
- Initial protection of ingredients in stomach environs
- Pre-dissolution of active ingredients results in enhanced bioavailability and release characteristics
- Enhanced bioavailability can lessen dose, lower costs, and enhance compliance.
- Effective, convenient, non-invasive oral delivery option for otherwise poorly absorbed and utilized nutraceuticals and pharmaceuticals
- Studies show consumers prefer easy-to-swallow soft gelatin capsules!
- Proven history of safe and effective use.
|
NanoSorb® Subligual Spray™
BioPharma Scientific® has applied its NanoSorb® technology for providing yet another more efficient means of delivering nutrients to the body.
Conventional pills, tablets, and liquids must travel through the digestive system in order to deliver active ingredients to the body. With NanoSorb® Sublingual Spray, the NanoSorb® suspension is sprayed into the mouth and under the tongue. The NanoSorb® liposomes penetrate the mucosal tissue of the mouth, and the nutrients spread throughout the body in minutes. This delivery system also bypasses the potentially degrading effects of the digestive system and liver.
|
| 
Revolutionary NanoSorb® Sublingual Spray: Faster, easier, and more effective than tablets and capsules |
| 
NanoSorb®'s sublingual nanotechnology application easily delivers nutrients directly into the bloodstream, bypassing the digestive tract for faster absorption with less potential inactivation. |
